Comparison of TEG 5000 and ROTEM Delta parameters and their interpretation and physiological correlation to the phase of hemostasis
| Parameters . | Interpretation . | Physiological correlation to phase of hemostasis . | |
|---|---|---|---|
| TEG 5000 (units) . | ROTEM Delta (units) . | ||
| Reaction rate (R) (min) | Clotting time (CT) (s) | Time for the trace to reach an amplitude of 2 mm | Activation of coagulation, thrombin generation, time to initial clot formation, and influence of anticoagulants |
| Kinetics time (K) (min) | Clot formation time (CFT) (s) | Time for the clot amplitude to reach from 2 mm to 20 mm | Fibrin activation and polymerization (ie, speed of clot propagation) |
| Angle (α) (degrees) | Angle (α) (degrees) | Angle created by drawing a tangent line from the point of clot initiation (R or CT) to the slope of the developing curve | Fibrin activation and polymerization (ie, speed of clot propagation) |
| N/A | A10 (mm) | Amplitude reached 10 min after CT | Fibrinogen and platelet contribution to the strength of the clot |
| Maximum amplitude (MA) (mm) | Maximum clot firmness (MCF) (mm) | Peak amplitude or strength of the clot | Fibrinogen and platelet contribution to the strength of the clot |
| Lysis 30 (LY 30) (%) | Lysis index 30 (LI 30) (%) | TEG: Percentage reduction in the area under the TEG curve (assuming MA remains constant) that occurs 30 min after MA is reachedROTEM: Percentage clot remaining (compared with MCF) when amplitude is measured 30 min after CT is detected | Fibrinolysis |
| Lysis 60 (LY 60) (%) | N/A | Percentage reduction in the area under the TEG curve (assuming MA remains constant) that occurs 60 min after MA is reached | Fibrinolysis |
| N/A | Maximum lysis (ML) (%) | Degree of fibrinolysis relative to MCF achieved during the measurement (percentage clot firmness lost). It is not calculated at a fixed time. | Fibrinolysis |
| Parameters . | Interpretation . | Physiological correlation to phase of hemostasis . | |
|---|---|---|---|
| TEG 5000 (units) . | ROTEM Delta (units) . | ||
| Reaction rate (R) (min) | Clotting time (CT) (s) | Time for the trace to reach an amplitude of 2 mm | Activation of coagulation, thrombin generation, time to initial clot formation, and influence of anticoagulants |
| Kinetics time (K) (min) | Clot formation time (CFT) (s) | Time for the clot amplitude to reach from 2 mm to 20 mm | Fibrin activation and polymerization (ie, speed of clot propagation) |
| Angle (α) (degrees) | Angle (α) (degrees) | Angle created by drawing a tangent line from the point of clot initiation (R or CT) to the slope of the developing curve | Fibrin activation and polymerization (ie, speed of clot propagation) |
| N/A | A10 (mm) | Amplitude reached 10 min after CT | Fibrinogen and platelet contribution to the strength of the clot |
| Maximum amplitude (MA) (mm) | Maximum clot firmness (MCF) (mm) | Peak amplitude or strength of the clot | Fibrinogen and platelet contribution to the strength of the clot |
| Lysis 30 (LY 30) (%) | Lysis index 30 (LI 30) (%) | TEG: Percentage reduction in the area under the TEG curve (assuming MA remains constant) that occurs 30 min after MA is reachedROTEM: Percentage clot remaining (compared with MCF) when amplitude is measured 30 min after CT is detected | Fibrinolysis |
| Lysis 60 (LY 60) (%) | N/A | Percentage reduction in the area under the TEG curve (assuming MA remains constant) that occurs 60 min after MA is reached | Fibrinolysis |
| N/A | Maximum lysis (ML) (%) | Degree of fibrinolysis relative to MCF achieved during the measurement (percentage clot firmness lost). It is not calculated at a fixed time. | Fibrinolysis |
N/A, corresponding parameter not available on the analyzer; ROTEM, rotational thromboelastometry; TEG, thromboelastography.