Active chimeric antigen receptor T-cell clinical trials for acute myeloid leukemia
| Target . | ClinicalTrials.gov identifier . | Institution/sponsor . | Age restriction . | Status . |
|---|---|---|---|---|
| CD7 | NCT04033302 | Shenzhen Geno-Immune Medical Institute | 6 mo-75 y | Recruiting |
| CD33 | NCT03971799 | Center for International Blood and Marrow Transplant Research | 1-30 y | Recruiting |
| CD44v6 | NCT04097301 | Horizon 2020/MolMed | 1-75 y | Recruiting |
| CD123 | NCT02159495NCT03766126NCT04109482NCT03190278NCT04318678 | City of Hope Medical CenterUniversity of PennsylvaniaMustang BioCellectisSt. Jude Children’s Research Hospital | >12 y>18 y>18 y18-64 y<21 y | RecruitingRecruitingRecruitingRecruitingRecruiting |
| NKG2D | NCT04167696NCT03018405 | Celyad OncologyCelyad Oncology | >18 y>18 y | RecruitingRecruiting |
| FLT3 | NCT03904069 | Amgen | >12 y | Not yet recruiting |
| CD123/CLL1 | NCT03631576 | Fujian Medical University | <70 y | Recruiting |
| CD123/CD33 | NCT04156256 | iCell Gene Therapeutics | None | Recruiting |
| CCL1/CD22/CD123 | NCT04010877 | Shenzhen Geno-Immune Medical Institute | 6 mo-75 y | Recruiting |
| Muc1/CLL1/CD22/CD38/CD56/CD123 | NCT03222674 | Shenzhen Geno-Immune Medical Institute | 2-75 y | Recruiting |
| CD33/CD28/CD56/CD123/CD117/CD133/CD34/Muc1 | NCT03473457 | Zhujiang Hospital | >6 mo | Recruiting |
| Target . | ClinicalTrials.gov identifier . | Institution/sponsor . | Age restriction . | Status . |
|---|---|---|---|---|
| CD7 | NCT04033302 | Shenzhen Geno-Immune Medical Institute | 6 mo-75 y | Recruiting |
| CD33 | NCT03971799 | Center for International Blood and Marrow Transplant Research | 1-30 y | Recruiting |
| CD44v6 | NCT04097301 | Horizon 2020/MolMed | 1-75 y | Recruiting |
| CD123 | NCT02159495NCT03766126NCT04109482NCT03190278NCT04318678 | City of Hope Medical CenterUniversity of PennsylvaniaMustang BioCellectisSt. Jude Children’s Research Hospital | >12 y>18 y>18 y18-64 y<21 y | RecruitingRecruitingRecruitingRecruitingRecruiting |
| NKG2D | NCT04167696NCT03018405 | Celyad OncologyCelyad Oncology | >18 y>18 y | RecruitingRecruiting |
| FLT3 | NCT03904069 | Amgen | >12 y | Not yet recruiting |
| CD123/CLL1 | NCT03631576 | Fujian Medical University | <70 y | Recruiting |
| CD123/CD33 | NCT04156256 | iCell Gene Therapeutics | None | Recruiting |
| CCL1/CD22/CD123 | NCT04010877 | Shenzhen Geno-Immune Medical Institute | 6 mo-75 y | Recruiting |
| Muc1/CLL1/CD22/CD38/CD56/CD123 | NCT03222674 | Shenzhen Geno-Immune Medical Institute | 2-75 y | Recruiting |
| CD33/CD28/CD56/CD123/CD117/CD133/CD34/Muc1 | NCT03473457 | Zhujiang Hospital | >6 mo | Recruiting |
Summary of active and completed clinical trials according to www.clinicaltrials.gov as of 1 June 2020.