Summary of findings reported from prospective studies of PE diagnosis in pregnancy
| Study . | Site of recruitment . | Assessment of PTP . | D-dimer assay and cutoff . | Prevalence of PE at presentation, % . | Prevalence of PE once CTPA was indicated, % . | CTPA avoided, % . | Subsequent VTE diagnosed during follow-up in those who avoided CTPA based on PTP and D-dimer . |
|---|---|---|---|---|---|---|---|
| Righini et al16 | Emergency | Revised Geneva | Vidas assay <500 μg/L | 7.1 | 6.1 | 14.2 | 0 (0%) of 46* (95% CI, 0% to 8%) |
| van der Pol et al17 | Emergency and obstetrical unit | YEARS | Various sensitive D-dimer assays using selective cutoffs at 500 and 1000 μg/L | 4 | 5.4 | 39 | 1 (0.51%) of 195† (95% CI, 0.09% to 2.9%) |
| Study . | Site of recruitment . | Assessment of PTP . | D-dimer assay and cutoff . | Prevalence of PE at presentation, % . | Prevalence of PE once CTPA was indicated, % . | CTPA avoided, % . | Subsequent VTE diagnosed during follow-up in those who avoided CTPA based on PTP and D-dimer . |
|---|---|---|---|---|---|---|---|
| Righini et al16 | Emergency | Revised Geneva | Vidas assay <500 μg/L | 7.1 | 6.1 | 14.2 | 0 (0%) of 46* (95% CI, 0% to 8%) |
| van der Pol et al17 | Emergency and obstetrical unit | YEARS | Various sensitive D-dimer assays using selective cutoffs at 500 and 1000 μg/L | 4 | 5.4 | 39 | 1 (0.51%) of 195† (95% CI, 0.09% to 2.9%) |
PTP, pretest probability; VTE, venous thromboembolism.
Two patients were receiving anticoagulation.
†Unknown if any patient was receiving anticoagulation.