Epitope homology with other human coronaviruses
SARS-CoV-2 epitope identified . | Other human coronavirus . | Protein name . | Amino acid sequence alignment . |
---|---|---|---|
Membrane | |||
LRGHLRIAGHHLGRC | LRGHLRIAGHHLGRC | ||
SARS coronavirus | M protein | RGHLRMAGHPLGRC | |
HKU1 | Membrane glycoprotein | RGHLYIQGVKLG | |
MERS | M protein | GHLKIAGMHFGAC | |
LRIAGHHLGRCDIKD | LRIAGHHLGRCDIKD | ||
SARS coronavirus | Membrane protein | LRMAGHPLGRCDIKD | |
SRTLSYYKLGASQRV | SRTLSYYKLGASQRV | ||
SARS coronavirus | Membrane protein | SRTLSYYKLGASQRV | |
SYYKLGASQRVAGDS | SYYKLGASQRVAGDS | ||
SARS coronavirus | Membrane protein | SYYKLGASQRVGTDS | |
LGASQRVAGDSGFAA | LGASQRVAGDSGFAA | ||
SARS Coronavirus | Membrane glycoprotein | LGASQRVGTDSGFAA | |
NL63 | Orf1a protein | LGAS–VTEDVKFAA | |
Nucleocapsid | |||
KPRQKRTATKAYNVT | KPRQKRTATKAYNVT | ||
SARS coronavirus | Nucleocapsid protein | KPRQKRTATKQYNVT | |
OC43 | Nucleocapsid protein | KPRQKRSPNK | |
NL63 | Chain A, nucleocapsid | KPRWKRVPTREENV | |
MERS | Nucleocapsid protein | RHKRVATKSFNV | |
AFFGMSRIGMEVTPS | AFFGMSRIGMEVTPS | ||
SARS coronavirus | Nucleocapsid protein N | AFFGMSRIGMEVTPS | |
MSRIGMEVTPSGTWL | MSRIGMEVTPSGTWL | ||
SARS coronavirus | Nucleocapsid protein | MSRIGMEVTPSGTWL | |
GMEVTPSGTWLTYTG | GMEVTPSGTWLTYTG | ||
SARS coronavirus | Nucleocapsid protein | GMEVTPSGTWLTY | |
Spike | |||
PFFSNVTWFHAIHVS | — | — | — |
NVTWFHAIHVSGTNG | — | — | — |
SKHTPINLVRDLPQG | SKHTPINLVRDLPQG | ||
OC43 | Replicase polyprotein 1ab | PANIV—LPQG | |
SARS coronavirus | S1 protein | PIDVVRDLPSG | |
PINLVRDLPQGFSAL | PINLVRDLPQGFSAL | ||
SARS coronavirus | Chain A, spike | PIDVVRDLPSGFNTL | |
OC43 | Replicase polyprotein 1ab | PANIV–LPQG | |
YNYLYRLFRKSNLKP | YNYLYRLFRKSNLKP | ||
SARS coronavirus | Chain E, spike glycoprotein | YNYKYRYLRHGKLRP |
SARS-CoV-2 epitope identified . | Other human coronavirus . | Protein name . | Amino acid sequence alignment . |
---|---|---|---|
Membrane | |||
LRGHLRIAGHHLGRC | LRGHLRIAGHHLGRC | ||
SARS coronavirus | M protein | RGHLRMAGHPLGRC | |
HKU1 | Membrane glycoprotein | RGHLYIQGVKLG | |
MERS | M protein | GHLKIAGMHFGAC | |
LRIAGHHLGRCDIKD | LRIAGHHLGRCDIKD | ||
SARS coronavirus | Membrane protein | LRMAGHPLGRCDIKD | |
SRTLSYYKLGASQRV | SRTLSYYKLGASQRV | ||
SARS coronavirus | Membrane protein | SRTLSYYKLGASQRV | |
SYYKLGASQRVAGDS | SYYKLGASQRVAGDS | ||
SARS coronavirus | Membrane protein | SYYKLGASQRVGTDS | |
LGASQRVAGDSGFAA | LGASQRVAGDSGFAA | ||
SARS Coronavirus | Membrane glycoprotein | LGASQRVGTDSGFAA | |
NL63 | Orf1a protein | LGAS–VTEDVKFAA | |
Nucleocapsid | |||
KPRQKRTATKAYNVT | KPRQKRTATKAYNVT | ||
SARS coronavirus | Nucleocapsid protein | KPRQKRTATKQYNVT | |
OC43 | Nucleocapsid protein | KPRQKRSPNK | |
NL63 | Chain A, nucleocapsid | KPRWKRVPTREENV | |
MERS | Nucleocapsid protein | RHKRVATKSFNV | |
AFFGMSRIGMEVTPS | AFFGMSRIGMEVTPS | ||
SARS coronavirus | Nucleocapsid protein N | AFFGMSRIGMEVTPS | |
MSRIGMEVTPSGTWL | MSRIGMEVTPSGTWL | ||
SARS coronavirus | Nucleocapsid protein | MSRIGMEVTPSGTWL | |
GMEVTPSGTWLTYTG | GMEVTPSGTWLTYTG | ||
SARS coronavirus | Nucleocapsid protein | GMEVTPSGTWLTY | |
Spike | |||
PFFSNVTWFHAIHVS | — | — | — |
NVTWFHAIHVSGTNG | — | — | — |
SKHTPINLVRDLPQG | SKHTPINLVRDLPQG | ||
OC43 | Replicase polyprotein 1ab | PANIV—LPQG | |
SARS coronavirus | S1 protein | PIDVVRDLPSG | |
PINLVRDLPQGFSAL | PINLVRDLPQGFSAL | ||
SARS coronavirus | Chain A, spike | PIDVVRDLPSGFNTL | |
OC43 | Replicase polyprotein 1ab | PANIV–LPQG | |
YNYLYRLFRKSNLKP | YNYLYRLFRKSNLKP | ||
SARS coronavirus | Chain E, spike glycoprotein | YNYKYRYLRHGKLRP |
Boldface type indicates a strong binder (< 2).
MERS, Middle East respiratory syndrome.