Acute GVHD organ involvement in the first 180 days after transplant
| Day 180 maximum grade, N . | Organ stage* . |
|---|---|
| Grade I (n = 4) | Skin stage 1 (n = 4) |
| Grade II (n = 59) | Upper GI only (n = 17) |
| Upper GI and lower GI (n = 13) | |
| • 12 stage 1 | |
| • 1 stage 2 | |
| Upper GI and skin stage 1-2 (n = 11) | |
| Upper GI, lower GI stage 1-2 and skin stage 1-2 (n = 7): | |
| • 4 lower GI stage 2 and skin stage 2 | |
| • 3 lower GI stage 1 and skin stage 1-2 | |
| Skin only, stage 2 (n = 7) | |
| Lower GI only, stage 1-2 (n = 4) | |
| • 3 stage 1 | |
| • 1 stage 2 | |
| Grade III (n = 15) | Skin stage 3, upper GI and lower GI stage 1-2 (n = 5) |
| • 4 skin stage 3, upper GI and lower GI stage 1 | |
| • 1 skin stage 3, upper GI and lower GI stage 2 | |
| Skin stage 3 and upper GI (n = 4) | |
| Skin stage 3 (n = 2) | |
| Skin stage 3 and liver stage 1 (n = 1) | |
| Lower GI stage 3 and skin stage 1 (n = 1) | |
| Lower GI stage 3 and upper GI (n = 1) | |
| Lower GI stage 3 and upper GI & skin stage 1 (n = 1) | |
| Grade IV (n = 7) | Lower GI stage 4 and upper GI (n = 2) |
| Lower GI stage 4, upper GI, and liver stage 1 or 3 (n = 2) | |
| Lower GI stage 4, upper GI, skin stage 2-3, and liver stage 2-3 (n = 2) | |
| Lower GI stage 4, upper GI, and skin stage 2 (n = 1) |
| Day 180 maximum grade, N . | Organ stage* . |
|---|---|
| Grade I (n = 4) | Skin stage 1 (n = 4) |
| Grade II (n = 59) | Upper GI only (n = 17) |
| Upper GI and lower GI (n = 13) | |
| • 12 stage 1 | |
| • 1 stage 2 | |
| Upper GI and skin stage 1-2 (n = 11) | |
| Upper GI, lower GI stage 1-2 and skin stage 1-2 (n = 7): | |
| • 4 lower GI stage 2 and skin stage 2 | |
| • 3 lower GI stage 1 and skin stage 1-2 | |
| Skin only, stage 2 (n = 7) | |
| Lower GI only, stage 1-2 (n = 4) | |
| • 3 stage 1 | |
| • 1 stage 2 | |
| Grade III (n = 15) | Skin stage 3, upper GI and lower GI stage 1-2 (n = 5) |
| • 4 skin stage 3, upper GI and lower GI stage 1 | |
| • 1 skin stage 3, upper GI and lower GI stage 2 | |
| Skin stage 3 and upper GI (n = 4) | |
| Skin stage 3 (n = 2) | |
| Skin stage 3 and liver stage 1 (n = 1) | |
| Lower GI stage 3 and skin stage 1 (n = 1) | |
| Lower GI stage 3 and upper GI (n = 1) | |
| Lower GI stage 3 and upper GI & skin stage 1 (n = 1) | |
| Grade IV (n = 7) | Lower GI stage 4 and upper GI (n = 2) |
| Lower GI stage 4, upper GI, and liver stage 1 or 3 (n = 2) | |
| Lower GI stage 4, upper GI, skin stage 2-3, and liver stage 2-3 (n = 2) | |
| Lower GI stage 4, upper GI, and skin stage 2 (n = 1) |
All upper GI involvement is stage 1 by definition.