Univariate CSH analysis of TTP
| Protein . | Cutoff . | Group . | n . | TTP . | ||
|---|---|---|---|---|---|---|
| HR (95% CI) . | Median TTP (range), mo . | P . | ||||
| Cereblon | 0.045 | H | 142 | 0.33 (0.15-0.75) | NR (55-NR) | .008 |
| L | 10 | 36 (8-NR) | ||||
| Aiolos | 0.351 | H | 43 | 1.74 (1.02-2.98) | 51 (31-NR) | .044 |
| L | 109 | NR (55-NR) | ||||
| Ikaros | 4.647 | H | 24 | 2.05 (1.12-3.74) | 42 (26-NR) | .020 |
| L | 128 | NR (55-NR) | ||||
| AGO2 | 3.510 | H | 12 | 2.60 (1.32-5.14) | 42 (25-52) | .006 |
| L | 156 | NR (59-NR) | ||||
| IRF4 | 0.539 | H | 113 | 0.57 (0.34-0.97) | NR (55-NR) | .039 |
| L | 41 | 49 (36-NR) | ||||
| PSMA3 | 3.985 | H | 17 | 1.78 (0.90-3.53) | 48 (55-NR) | .096 |
| L | 141 | NR (54.87-NR) | ||||
| PSME1 | 0.981 | H | 107 | 1.48 (0.81-2.69) | 55 (51-NR) | .2 |
| L | 45 | NR (51-NR) | ||||
| PSMD1 | 3.458 | H | 10 | 3.43 (1.67-7.02) | 40 (8-51) | <.001 |
| L | 148 | NR (59-NR) | ||||
| PSMD4 | 0.507 | H | 34 | 1.86 (1.08-3.21) | 48 (35-NR) | .026 |
| L | 124 | NR (59-NR) | ||||
| PSMD10 | 0.548 | H | 115 | 2.46 (1.17-5.19) | 53 (48-NR) | .018 |
| L | 37 | NR (55-NR) | ||||
| GCR | 0.655 | H | 139 | 2.96 (0.72-12.12) | 59 (51-NR) | .131 |
| L | 13 | NR (NR-NR) | ||||
| XPO1 | 2.453 | H | 91 | 1.47 (0.86-2.52) | 53 (48-NR) | .156 |
| L | 63 | NR (59-NR) | ||||
| Protein . | Cutoff . | Group . | n . | TTP . | ||
|---|---|---|---|---|---|---|
| HR (95% CI) . | Median TTP (range), mo . | P . | ||||
| Cereblon | 0.045 | H | 142 | 0.33 (0.15-0.75) | NR (55-NR) | .008 |
| L | 10 | 36 (8-NR) | ||||
| Aiolos | 0.351 | H | 43 | 1.74 (1.02-2.98) | 51 (31-NR) | .044 |
| L | 109 | NR (55-NR) | ||||
| Ikaros | 4.647 | H | 24 | 2.05 (1.12-3.74) | 42 (26-NR) | .020 |
| L | 128 | NR (55-NR) | ||||
| AGO2 | 3.510 | H | 12 | 2.60 (1.32-5.14) | 42 (25-52) | .006 |
| L | 156 | NR (59-NR) | ||||
| IRF4 | 0.539 | H | 113 | 0.57 (0.34-0.97) | NR (55-NR) | .039 |
| L | 41 | 49 (36-NR) | ||||
| PSMA3 | 3.985 | H | 17 | 1.78 (0.90-3.53) | 48 (55-NR) | .096 |
| L | 141 | NR (54.87-NR) | ||||
| PSME1 | 0.981 | H | 107 | 1.48 (0.81-2.69) | 55 (51-NR) | .2 |
| L | 45 | NR (51-NR) | ||||
| PSMD1 | 3.458 | H | 10 | 3.43 (1.67-7.02) | 40 (8-51) | <.001 |
| L | 148 | NR (59-NR) | ||||
| PSMD4 | 0.507 | H | 34 | 1.86 (1.08-3.21) | 48 (35-NR) | .026 |
| L | 124 | NR (59-NR) | ||||
| PSMD10 | 0.548 | H | 115 | 2.46 (1.17-5.19) | 53 (48-NR) | .018 |
| L | 37 | NR (55-NR) | ||||
| GCR | 0.655 | H | 139 | 2.96 (0.72-12.12) | 59 (51-NR) | .131 |
| L | 13 | NR (NR-NR) | ||||
| XPO1 | 2.453 | H | 91 | 1.47 (0.86-2.52) | 53 (48-NR) | .156 |
| L | 63 | NR (59-NR) | ||||
Bold indicates statistically significant P values (P < .05).
CI, confidence interval; NR, not reached.