Treatment-related AEs (grade 1/2 observed in >1 patient and grade 3/4 observed in any patient)
| . | Toxicity, no. of patients (%) . | |||
|---|---|---|---|---|
| Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . | |
| Neutropenia | 1 (5) | 2 (10) | ||
| Thrombocytopenia | 1 (5) | 1 (5) | ||
| Anorexia | 2 (10) | |||
| AST elevation | 2 (10) | |||
| Cheilitis | 1 (5) | 1 (5) | ||
| Otalgia | 1 (5) | 1 (5) | ||
| Facial edema | 1 (5) | 1 (5) | ||
| Fatigue | 1 (5) | |||
| Fever | 6 (29) | |||
| Headache | 2 (10) | |||
| Infusion-related reaction | 4 (19) | 1 (5) | ||
| Myalgia | 2 (10) | |||
| Nasal congestion | 2 (10) | 2 (10) | ||
| Sore throat | 2 (10) | 1 (5) | ||
| . | Toxicity, no. of patients (%) . | |||
|---|---|---|---|---|
| Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . | |
| Neutropenia | 1 (5) | 2 (10) | ||
| Thrombocytopenia | 1 (5) | 1 (5) | ||
| Anorexia | 2 (10) | |||
| AST elevation | 2 (10) | |||
| Cheilitis | 1 (5) | 1 (5) | ||
| Otalgia | 1 (5) | 1 (5) | ||
| Facial edema | 1 (5) | 1 (5) | ||
| Fatigue | 1 (5) | |||
| Fever | 6 (29) | |||
| Headache | 2 (10) | |||
| Infusion-related reaction | 4 (19) | 1 (5) | ||
| Myalgia | 2 (10) | |||
| Nasal congestion | 2 (10) | 2 (10) | ||
| Sore throat | 2 (10) | 1 (5) | ||
AST, aspartate aminotransferase.