Table 1.

Cell population frequencies (%) in human tissues

TissueCD27CD27+TransitionalCD19+ lymphocytesPlasmablastsGCTotal CD19+
CD38 intCD38 hi
Spleen 29.61 70.39 2.24 62.08 1.00 0.81 0.10 51.93 
14.19 14.19 2.06 11.02 1.06 1.90 0.11 13.59 
10.4-74.8 25.2-89.6 0.3-10.7 39.8-78.6 0.1-4.0 0.04-10.9 0.003-0.4 14.4-74.4 
Blood 79.63 20.37 3.62 24.85 0.24 0.69 0.13 7.39 
13.07 13.07 1.87 18.12 0.25 0.63 0.18 6.15 
52.2-97.3 2.7-47.8 0.8-5.9 2.6-72.9 0.02-0.9 0.09-2.4 0-0.6 1.6-19.2 
BM 54.00 46.00 4.00 20.74 0.51 0.42 0.12 10.69 
20.79 20.79 2.83 16.40 0.50 0.42 0.15 6.87 
12.8-93.5 6.5-87.2 0.5-9.2 4.0-58.7 0.03-1.4 0.04-1.7 0-0.5 2.8-27.7 
Gut 13.56 86.44 0.80 28.17 1.92 0.29 0.12 22.74 
11.85 11.85 0.73 19.80 1.30 0.22 0.13 16.00 
3.6-50.2 49.8-96.4 0.05-2.0 3.2-70.1 0.03-3.5 0.04-0.8 0-0.4 1.6-53.8 
TissueCD27CD27+TransitionalCD19+ lymphocytesPlasmablastsGCTotal CD19+
CD38 intCD38 hi
Spleen 29.61 70.39 2.24 62.08 1.00 0.81 0.10 51.93 
14.19 14.19 2.06 11.02 1.06 1.90 0.11 13.59 
10.4-74.8 25.2-89.6 0.3-10.7 39.8-78.6 0.1-4.0 0.04-10.9 0.003-0.4 14.4-74.4 
Blood 79.63 20.37 3.62 24.85 0.24 0.69 0.13 7.39 
13.07 13.07 1.87 18.12 0.25 0.63 0.18 6.15 
52.2-97.3 2.7-47.8 0.8-5.9 2.6-72.9 0.02-0.9 0.09-2.4 0-0.6 1.6-19.2 
BM 54.00 46.00 4.00 20.74 0.51 0.42 0.12 10.69 
20.79 20.79 2.83 16.40 0.50 0.42 0.15 6.87 
12.8-93.5 6.5-87.2 0.5-9.2 4.0-58.7 0.03-1.4 0.04-1.7 0-0.5 2.8-27.7 
Gut 13.56 86.44 0.80 28.17 1.92 0.29 0.12 22.74 
11.85 11.85 0.73 19.80 1.30 0.22 0.13 16.00 
3.6-50.2 49.8-96.4 0.05-2.0 3.2-70.1 0.03-3.5 0.04-0.8 0-0.4 1.6-53.8 

For each tissue, from top to bottom, shown are the mean, standard deviation, and range of the percentages of listed populations among parent gates. For CD19+ cells, the parent gates are lymphocytes or total events, shown separately. For CD27, CD27+, and transitional cells, the parent gate is CD19+ lymphocytes. Plasmablasts are gated from all live single cells and GC cells from all live single CD19+ IgD CD10+ cells.

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