Clinical characteristics of multiple myeloma patients (immunoglobulins used in osteoclast assays)
| Characteristic . | Isolation of the M component . | Isolation of uninvolved immunoglobulins . | ||
|---|---|---|---|---|
| Without BD (n = 10) . | With BD (n = 16) . | Without BD (n = 10) . | With BD (n = 17) . | |
| Age (median), y | 67.7 (44-78) | 67 (49-79) | 70.1 (61-78) | 62.7 (30-81) |
| Sex (male) | 7 (70%) | 6 (38%) | 7 (70%) | 11 (64.7%) |
| Female | 3 | 10 | 3 | 6 |
| ISS 1 | 6 | 3 | 3 | 4 |
| ISS 2 | 3 | 1 | 4 | 5 |
| ISS 3 | 1 | 2 | 2 | |
| Unknown | 0 | 12 | 1 | 6 |
| HB, g/L | 12.1 (9.3-13.8) | 11.0 (6.3-14.2) | 10.9 (8.8-14.3) | 10.2 (5.9-14.9) |
| WBC (/L) | 5.5 (2.2-11.3) | 4.8 (1.8-8.1) | 8.8 (3.8-13.2) | 8.4 (3.2-14.9) |
| TRC (/L) | 264 (154-406) | 191 (5-296) | 229 (129-336) | 233 (120-412) |
| M component, g/L | 20.8 (3.5-42) | 29.9 (8-71.9) | 23.8 (2.5-44) | 21.9 (0-63) |
| % PC | 20 (9-44) | 35 (2-95) | 35 (10-65) | 41 (6-83) |
| Light chain κ | 5 (50%) | 12 (75%) | 10 (100%) | 13 (76.4%)* |
| Characteristic . | Isolation of the M component . | Isolation of uninvolved immunoglobulins . | ||
|---|---|---|---|---|
| Without BD (n = 10) . | With BD (n = 16) . | Without BD (n = 10) . | With BD (n = 17) . | |
| Age (median), y | 67.7 (44-78) | 67 (49-79) | 70.1 (61-78) | 62.7 (30-81) |
| Sex (male) | 7 (70%) | 6 (38%) | 7 (70%) | 11 (64.7%) |
| Female | 3 | 10 | 3 | 6 |
| ISS 1 | 6 | 3 | 3 | 4 |
| ISS 2 | 3 | 1 | 4 | 5 |
| ISS 3 | 1 | 2 | 2 | |
| Unknown | 0 | 12 | 1 | 6 |
| HB, g/L | 12.1 (9.3-13.8) | 11.0 (6.3-14.2) | 10.9 (8.8-14.3) | 10.2 (5.9-14.9) |
| WBC (/L) | 5.5 (2.2-11.3) | 4.8 (1.8-8.1) | 8.8 (3.8-13.2) | 8.4 (3.2-14.9) |
| TRC (/L) | 264 (154-406) | 191 (5-296) | 229 (129-336) | 233 (120-412) |
| M component, g/L | 20.8 (3.5-42) | 29.9 (8-71.9) | 23.8 (2.5-44) | 21.9 (0-63) |
| % PC | 20 (9-44) | 35 (2-95) | 35 (10-65) | 41 (6-83) |
| Light chain κ | 5 (50%) | 12 (75%) | 10 (100%) | 13 (76.4%)* |
% PC, % plasma cells; ISS, International Staging System; HB, hemoglobin; TRC, number of thrombocytes; WBC, white blood cells.
The rest is nonsecretory.