Patient characteristics by receipt of transfusion (N = 350)
| Characteristic . | RBC transfusion . | |||
|---|---|---|---|---|
| No transfusion (n = 267) . | 1-U transfusion (n = 49) . | 2- to 3-U transfusion (n = 34) . | P* . | |
| Age, median (IQR), y | 61 (20-86) | 58 (24-76) | 57 (24-75) | .18 |
| Female sex, n (%) | 154 (58) | 31 (63) | 21 (62) | .72 |
| Male sex, n (%) | 113 (42) | 18 (37) | 13 (38) | |
| Race, n (%) | ||||
| Black/African American | 181 (68) | 37 (76) | 25 (74) | .73 |
| White/Caucasian | 72 (27) | 10 (20) | 9 (26) | |
| Other | 14 (4) | 2 (4) | 0 (0) | |
| Do not know/refused | 3 (1) | 0 (0) | 0 (0) | |
| Ethnicity, n (%) | ||||
| Not Hispanic or Latino | 250 (94) | 47 (96) | 32 (94) | .89 |
| Hispanic or Latino | 14 (5) | 2 (4) | 2 (6) | |
| Do not know/refused to answer | 3 (1) | 0 (0) | 0 (0) | |
| Nadir Hb, median (IQR), g/dL | 8.2 (6.0-10.0) | 6.7 (6.1-7.3) | 6.6 (5.7-7.1) | <.01 |
| Nadir Hb (categorical), n (%) | ||||
| 9-10 g/dL | 76 (29) | 0 (0) | 1 (3) | <.01 |
| 8-8.9 g/dL | 86 (32) | 1 (2) | 0 (0) | |
| 7-7.9 g/dL | 81 (30) | 4 (8) | 4 (12) | |
| <7 g/dL | 24 (9) | 44 (90) | 29 (85) | |
| Fatigability, median (IQR)† | ||||
| Baseline in-hospital | 30 (8-45) | 30 (17-42) | 35 (20-44) | .33 |
| 7-d follow-up | 32 (0-50) | 33 (19-43 | 33 (17-43) | .76 |
| Fatigue, median (IQR)† | ||||
| Baseline in-hospital | 27 (8-40) | 28 (14-39) | 26 (17-39) | .71 |
| 7-d follow-up | 44 (25-55) | 42 (26-53) | 43 (36-54) | .54 |
| Physical function, median (IQR)† | ||||
| Baseline in-hospital | 45 (24-55) | 47 (28-54) | 43 (36-53) | .62 |
| 7-d follow-up | 44 (25-55) | 42 (26-53) | 43 (36-54) | .54 |
| Charlson Comorbidity Index, n (%) | ||||
| 0 | 44 (16) | 7 (14) | 7 (21) | .98 |
| 1-2 | 74 (28) | 14 (29) | 9 (26) | |
| 3-4 | 56 (21) | 10 (20) | 5 (15) | |
| ≥5 | 93 (35) | 18 (37) | 13 (38) | |
| Other comorbidities, n (%) | ||||
| Sickle cell anemia | 15 (6) | 6 (12) | 4 (12) | .14 |
| Iron-deficiency anemia | 33 (12) | 16 (33) | 9 (27) | <.01 |
| GIB | 10 (4) | 8 (16) | 12 (35) | <.01 |
| Length of stay, median (IQR), d | 6 (1-31) | 8 (3-16) | 9 (4-19) | .07 |
| Characteristic . | RBC transfusion . | |||
|---|---|---|---|---|
| No transfusion (n = 267) . | 1-U transfusion (n = 49) . | 2- to 3-U transfusion (n = 34) . | P* . | |
| Age, median (IQR), y | 61 (20-86) | 58 (24-76) | 57 (24-75) | .18 |
| Female sex, n (%) | 154 (58) | 31 (63) | 21 (62) | .72 |
| Male sex, n (%) | 113 (42) | 18 (37) | 13 (38) | |
| Race, n (%) | ||||
| Black/African American | 181 (68) | 37 (76) | 25 (74) | .73 |
| White/Caucasian | 72 (27) | 10 (20) | 9 (26) | |
| Other | 14 (4) | 2 (4) | 0 (0) | |
| Do not know/refused | 3 (1) | 0 (0) | 0 (0) | |
| Ethnicity, n (%) | ||||
| Not Hispanic or Latino | 250 (94) | 47 (96) | 32 (94) | .89 |
| Hispanic or Latino | 14 (5) | 2 (4) | 2 (6) | |
| Do not know/refused to answer | 3 (1) | 0 (0) | 0 (0) | |
| Nadir Hb, median (IQR), g/dL | 8.2 (6.0-10.0) | 6.7 (6.1-7.3) | 6.6 (5.7-7.1) | <.01 |
| Nadir Hb (categorical), n (%) | ||||
| 9-10 g/dL | 76 (29) | 0 (0) | 1 (3) | <.01 |
| 8-8.9 g/dL | 86 (32) | 1 (2) | 0 (0) | |
| 7-7.9 g/dL | 81 (30) | 4 (8) | 4 (12) | |
| <7 g/dL | 24 (9) | 44 (90) | 29 (85) | |
| Fatigability, median (IQR)† | ||||
| Baseline in-hospital | 30 (8-45) | 30 (17-42) | 35 (20-44) | .33 |
| 7-d follow-up | 32 (0-50) | 33 (19-43 | 33 (17-43) | .76 |
| Fatigue, median (IQR)† | ||||
| Baseline in-hospital | 27 (8-40) | 28 (14-39) | 26 (17-39) | .71 |
| 7-d follow-up | 44 (25-55) | 42 (26-53) | 43 (36-54) | .54 |
| Physical function, median (IQR)† | ||||
| Baseline in-hospital | 45 (24-55) | 47 (28-54) | 43 (36-53) | .62 |
| 7-d follow-up | 44 (25-55) | 42 (26-53) | 43 (36-54) | .54 |
| Charlson Comorbidity Index, n (%) | ||||
| 0 | 44 (16) | 7 (14) | 7 (21) | .98 |
| 1-2 | 74 (28) | 14 (29) | 9 (26) | |
| 3-4 | 56 (21) | 10 (20) | 5 (15) | |
| ≥5 | 93 (35) | 18 (37) | 13 (38) | |
| Other comorbidities, n (%) | ||||
| Sickle cell anemia | 15 (6) | 6 (12) | 4 (12) | .14 |
| Iron-deficiency anemia | 33 (12) | 16 (33) | 9 (27) | <.01 |
| GIB | 10 (4) | 8 (16) | 12 (35) | <.01 |
| Length of stay, median (IQR), d | 6 (1-31) | 8 (3-16) | 9 (4-19) | .07 |
IQR, interquartile range.
P value equals Kruskal-Wallis for continuous variables (age, Hb values, fatigability, fatigue, physical function, and length of stay) and χ2 for categorical variables (sex, race, ethnicity, Charlson Comorbidity Index, sickle cell anemia, iron deficiency, and GIB).
Scale ranges: Pittsburgh Fatigability Scale, 0 to 50; PROMIS-F, 8 to 40; PROMIS-PF, 11 to 55.