Table 3.

Genotype distribution of pups from intercrosses of Lman1+/− and Mcfd2+/− mice

GenotypeP, χ2
Lman1−/−Lman1+/− or Lman1+/+
Observed 48 217 <.01 
Expected 66 199 
 Mcfd2−/− Mcfd2+/− or Mcfd2+/+  
Observed 61 204 >.45 
Expected 66 199 
GenotypeP, χ2
Lman1−/−Lman1+/− or Lman1+/+
Observed 48 217 <.01 
Expected 66 199 
 Mcfd2−/− Mcfd2+/− or Mcfd2+/+  
Observed 61 204 >.45 
Expected 66 199 

Intercrosses between mice doubly heterozygous for Lman1-– and Mcfd2 were performed to generate double-null Lman1−/− mice, Mcfd2−/− mice, and littermate controls; 265 mice of the 9 possible expected genotypes were generated (Table 3).

or Create an Account

Close Modal
Close Modal