AML patient samples selected for cell sorting and xenotransplantation studies
AML . | CD200 (% of blasts) . | CD34 (% of blasts) . | CD45dimCD200+ (% of MNCs) . | CD200 sort . | Karyotype . | NPM1 . | FLT3-ITD . |
---|---|---|---|---|---|---|---|
AML samples expressing CD200 on ≥10% of blasts | |||||||
3 | 52 | 10 | 20 | Standard | Normal | Mutated | Positive |
5 | 70 | 21 | 28 | Standard | Normal | Mutated | Positive |
11 | 10 | 10 | 3 | Standard | Normal | Mutated | Negative |
13 | 25 | 3 | 4 | Standard | Normal | Mutated | Negative |
21 | 48 | 2 | 4 | Standard | Normal | Mutated | Negative |
22 | 35 | <1 | 35 | Standard | Normal | Mutated | Negative |
30 | 96 | 84 | 45 | Standard | Normal | WT | Negative |
47 | 85 | 75 | 40 | Standard | Abnormal | WT | Negative |
51 | 77 | 89 | 76 | Standard | Abnormal | WT | Negative |
63 | 77 | 35 | 85 | Standard | unknown | Mutated | Positive |
AML samples expressing CD200 on <5% of blasts | |||||||
27 | 1 | <1 | 1 | Standard | Normal | WT | Negative |
36 | <1 | <1 | <1 | Standard | Abnormal | Mutated | Negative |
38 | 4 | 4 | 2 | Standard | Abnormal | Mutated | Negative |
44 | 3 | 100 | 4 | Standard | Abnormal | WT | Negative |
45 | <1 | 90 | <1 | Standard | Abnormal | WT | Negative |
54 | <1 | <1 | <1 | Standard | Abnormal | WT | Negative |
AML samples with mixed leukemic and multilineage grafts | |||||||
7 | 42 | 5 | 2 | Expanded | Normal | Mutated | Negative |
2 | 61 | 15 | 16 | Expanded | Normal | Mutated | Positive |
AML . | CD200 (% of blasts) . | CD34 (% of blasts) . | CD45dimCD200+ (% of MNCs) . | CD200 sort . | Karyotype . | NPM1 . | FLT3-ITD . |
---|---|---|---|---|---|---|---|
AML samples expressing CD200 on ≥10% of blasts | |||||||
3 | 52 | 10 | 20 | Standard | Normal | Mutated | Positive |
5 | 70 | 21 | 28 | Standard | Normal | Mutated | Positive |
11 | 10 | 10 | 3 | Standard | Normal | Mutated | Negative |
13 | 25 | 3 | 4 | Standard | Normal | Mutated | Negative |
21 | 48 | 2 | 4 | Standard | Normal | Mutated | Negative |
22 | 35 | <1 | 35 | Standard | Normal | Mutated | Negative |
30 | 96 | 84 | 45 | Standard | Normal | WT | Negative |
47 | 85 | 75 | 40 | Standard | Abnormal | WT | Negative |
51 | 77 | 89 | 76 | Standard | Abnormal | WT | Negative |
63 | 77 | 35 | 85 | Standard | unknown | Mutated | Positive |
AML samples expressing CD200 on <5% of blasts | |||||||
27 | 1 | <1 | 1 | Standard | Normal | WT | Negative |
36 | <1 | <1 | <1 | Standard | Abnormal | Mutated | Negative |
38 | 4 | 4 | 2 | Standard | Abnormal | Mutated | Negative |
44 | 3 | 100 | 4 | Standard | Abnormal | WT | Negative |
45 | <1 | 90 | <1 | Standard | Abnormal | WT | Negative |
54 | <1 | <1 | <1 | Standard | Abnormal | WT | Negative |
AML samples with mixed leukemic and multilineage grafts | |||||||
7 | 42 | 5 | 2 | Expanded | Normal | Mutated | Negative |
2 | 61 | 15 | 16 | Expanded | Normal | Mutated | Positive |
FLT3-ITD, Fms-like tyrosine kinase 3–internal tandem duplication.