Frailty scores in ASPIRE, ENDEAVOR, and ARROW
| . | ASPIRE . | ENDEAVOR . | ARROW . | |||
|---|---|---|---|---|---|---|
| KRd27 mg/m2 (n = 396) . | Rd (n = 396) . | Kd56 mg/m2 (n = 464) . | Vd (n = 465) . | Once-weekly Kd70 mg/m2 (n = 240) . | Twice-weekly Kd27 mg/m2 (n = 238) . | |
| Age group, n (%), y | ||||||
| <75 | 353 (89) | 343 (87) | 387 (83) | 399 (86) | 194 (81) | 206 (87) |
| 75-80 | 33 (8) | 42 (11) | 60 (13) | 52 (11) | 35 (15) | 29 (12) |
| >80 | 10 (3) | 11 (3) | 17 (4) | 14 (3) | 11 (5) | 3 (1) |
| Modified CCI score, n (%) | ||||||
| ≤1 | 280 (71) | 258 (65) | 225 (48) | 230 (49) | 124 (52) | 138 (58) |
| >1 | 77 (19) | 97 (24) | 221 (48) | 222 (48) | 105 (44) | 92 (39) |
| Missing* | 39 (10) | 41 (10) | 18 (4) | 13 (3) | 11 (5) | 8 (3) |
| ECOG performance status at baseline, n (%) | ||||||
| 0 | 165 (42) | 175 (44) | 221 (48) | 232 (50) | 118 (49) | 118 (50) |
| 1 | 191 (48) | 186 (47) | 210 (45) | 203 (44) | 121 (50) | 120 (50) |
| ≥2 | 40 (10) | 35 (9) | 33 (7) | 30 (6) | 1 (<1) | 0 |
| Frailty score, n (%) | ||||||
| 0 (fit) | 115 (29) | 114 (29) | 110 (24) | 121 (26) | 60 (25) | 66 (28) |
| 1 (intermediate) | 149 (38) | 138 (35) | 168 (36) | 169 (36) | 89 (37) | 103 (43) |
| ≥2 (frail) | 93 (23) | 103 (26) | 168 (36) | 162 (35) | 80 (33) | 61 (26) |
| Missing* | 39 (10) | 41 (10) | 18 (4) | 13 (3) | 11 (5) | 8 (3) |
| . | ASPIRE . | ENDEAVOR . | ARROW . | |||
|---|---|---|---|---|---|---|
| KRd27 mg/m2 (n = 396) . | Rd (n = 396) . | Kd56 mg/m2 (n = 464) . | Vd (n = 465) . | Once-weekly Kd70 mg/m2 (n = 240) . | Twice-weekly Kd27 mg/m2 (n = 238) . | |
| Age group, n (%), y | ||||||
| <75 | 353 (89) | 343 (87) | 387 (83) | 399 (86) | 194 (81) | 206 (87) |
| 75-80 | 33 (8) | 42 (11) | 60 (13) | 52 (11) | 35 (15) | 29 (12) |
| >80 | 10 (3) | 11 (3) | 17 (4) | 14 (3) | 11 (5) | 3 (1) |
| Modified CCI score, n (%) | ||||||
| ≤1 | 280 (71) | 258 (65) | 225 (48) | 230 (49) | 124 (52) | 138 (58) |
| >1 | 77 (19) | 97 (24) | 221 (48) | 222 (48) | 105 (44) | 92 (39) |
| Missing* | 39 (10) | 41 (10) | 18 (4) | 13 (3) | 11 (5) | 8 (3) |
| ECOG performance status at baseline, n (%) | ||||||
| 0 | 165 (42) | 175 (44) | 221 (48) | 232 (50) | 118 (49) | 118 (50) |
| 1 | 191 (48) | 186 (47) | 210 (45) | 203 (44) | 121 (50) | 120 (50) |
| ≥2 | 40 (10) | 35 (9) | 33 (7) | 30 (6) | 1 (<1) | 0 |
| Frailty score, n (%) | ||||||
| 0 (fit) | 115 (29) | 114 (29) | 110 (24) | 121 (26) | 60 (25) | 66 (28) |
| 1 (intermediate) | 149 (38) | 138 (35) | 168 (36) | 169 (36) | 89 (37) | 103 (43) |
| ≥2 (frail) | 93 (23) | 103 (26) | 168 (36) | 162 (35) | 80 (33) | 61 (26) |
| Missing* | 39 (10) | 41 (10) | 18 (4) | 13 (3) | 11 (5) | 8 (3) |
No medical history available.