Table 4.

Inhibitor Eradication Trial: power simulations (n = 90)

Eradication rate in the emicizumab arm, %Power, %*
96.0 74 
96.3 79 
96.6 81 
96.9 82 
Eradication rate in the emicizumab arm, %Power, %*
96.0 74 
96.3 79 
96.6 81 
96.9 82 

There is 81% power to detect a difference of 96.6% between trial arms, with 90 subjects and α = 0.05.

*

This assumes the eradication rate in the ELOCTATE ITI arm is 80%.

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