Selected retrospective studies looking at outcome in women with lymphoma diagnosed during pregnancy
| Authors . | Study population . | T1, T2, and T3 . | Outcome/survival . | Fetal morbidity/mortality . |
|---|---|---|---|---|
| Evens et al19 | 90 patients: HL:50; NHL: 40 | T1, 12% | 3-y PFS and OS: 53% and 82% for NHL and 85% and 97% for HL, respectively | Gestation full term in 56% of cases; delivery at median of 37 wk; induction of labor in 33%; 6 patients underwent elective termination |
| T2, 58% | ||||
| T3, 38% | ||||
| Pinnix et al23 | 39 patients: HL 31; NHL 8 | T1, 8% | 5-y PFS and OS: 75% and 82%, respectively | Delivery at a median of 37 wk; 3 patients underwent elective termination; no fetal abnormalities were observed |
| T2, 67% | ||||
| T3, 25% | ||||
| Maggen et al22 | 134 patients with HL | 5-y PFS and OS: 82.6% and 97.3% for early stage HL and 90.9% and 100% for advanced HL, respectively | Preterm contractions (12%) and rupture of membranes (5%), higher in patients receiving antenatal treatment |
| Authors . | Study population . | T1, T2, and T3 . | Outcome/survival . | Fetal morbidity/mortality . |
|---|---|---|---|---|
| Evens et al19 | 90 patients: HL:50; NHL: 40 | T1, 12% | 3-y PFS and OS: 53% and 82% for NHL and 85% and 97% for HL, respectively | Gestation full term in 56% of cases; delivery at median of 37 wk; induction of labor in 33%; 6 patients underwent elective termination |
| T2, 58% | ||||
| T3, 38% | ||||
| Pinnix et al23 | 39 patients: HL 31; NHL 8 | T1, 8% | 5-y PFS and OS: 75% and 82%, respectively | Delivery at a median of 37 wk; 3 patients underwent elective termination; no fetal abnormalities were observed |
| T2, 67% | ||||
| T3, 25% | ||||
| Maggen et al22 | 134 patients with HL | 5-y PFS and OS: 82.6% and 97.3% for early stage HL and 90.9% and 100% for advanced HL, respectively | Preterm contractions (12%) and rupture of membranes (5%), higher in patients receiving antenatal treatment |
HL, Hodgkin lymphoma; NHL non-Hodgkin lymphoma; OS, overall survival; PFS, progression-free survival; T1, first trimester; T2, second trimester; T3, third trimester.