RT Journal Article
A1 Sola-Visner, Martha
T1 Cardiovascular disease and weight … at birth
JF Blood
JO Blood
YR 2011
DO 10.1182/blood-2011-06-361352
VO 118
IS 6
SP 1439
OP 1441
SN 0006-4971
AB Over the past 2 decades, multiple epidemiologic studies demonstrated that individuals born with low birth weight (LBW) are predisposed to cardiovascular disease and hypertension,1,2 but the cellular and molecular mechanisms underlying this association remained poorly understood. In this issue of Blood, Ligi and colleagues demonstrate that endothelial progenitors from LBW infants exhibit striking reductions in their angiogenic properties, compared with those from infants born with normal weight, thus providing for the first time a potential mechanistic link between LBW and adult hypertension (see figure).3
RD 11/15/2025
UL https://doi.org/10.1182/blood-2011-06-361352